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Pluronic P-123 is the tradename for a triblock copolymer manufactured by the BASF Corporation. The nominal chemical formula is HO(CH2CH2O)20(CH2CH(CH3)O)70(CH2CH2O)20H, which corresponds to a molecular weight of around 5800 Da. Triblock copolymers based on poly(ethylene glycol)-poly(propylene glycol)-poly(ethylene glycol) are known generically as poloxamer, and similar materials are manufactured by other companies. Poloxamers have behaviors similar to those of hydrocarbon surfactants, and will form micelles when placed in a selective solvent such as water. They are capable of forming both spherical and cylindrical micelles 〔 Wanka G, Hoffmann H, Ulbricht W, "Phase-Diagrams and Aggregation Behavior of Poly(Oxyethylene)-Poly(Oxypropylene)-Poly(Oxyethylene) Triblock Copolymers in Aqueous-Solutions", ''Macromolecules'', 1994, 27, 4145.〕 ==Uses== P-123 has recently been used in the synthesis of mesoporous materials including FDU-14.〔Wan Y, Zhao D, "On the Controllable Soft-Templating Approach to Mesoporous Silicates", ''Chem. Rev.'', 2007, 107, 2821.〕 Dissolved P-123 forms micelles that are used as the backbone to make structured mesoporous materials such as SBA-15. "Potential Degradation by Sonication" Wang et al. reported that aqueous solutions of poloxamer 188 (Pluronic® F-68) and poloxamer 407 (Pluronic® F-127) sonicated in the presence or absence of multi-walled carbon nanotubes (MWNTs) can became highly toxic to cultured cells. Moreover, toxicity correlated with the sonolytic degradation of the polymers. Wang et al., Nanotoxicology. 2013 Nov; vol 7: pages 1272–1281, doi: 10.3109/17435390.2012.736547 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657567/ 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Pluronic P-123」の詳細全文を読む スポンサード リンク
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